Juridical and Doctrinal issues have been an interesting topic in historical research in its entirety. Despite the amount of information, they provide, they have been considered, until recently, defunct and not approved. In this article, we will deal with the topic of the social and economic effects of epidemics and famines through doctrinal books. Such crises and pandemics affected people in general, and new incidents and situations appeared with them, which made the public stand unable to clarify the permissible from the forbidden. This intersects between what is religious, social and economic. Similarly, the opinion of the Shariah differs according to the issue raised in terms of its contexts and the parties involved. All of these matters will be addressed in this article.