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Hadhramout University Journal of Natural & Applied Sciences

Hadhramout University Journal of Natural & Applied Sciences

Abstract

This study was achieved at the industrial kidney centre in Qatan hospital during the period from February 2018 to July 2018, the study aimed at evaluating some hematological changes that occur in patients with chronic renal failure (CRF) undergoing hemodialysis and comparing them with healthy people. Blood samples of 55 cases of both sexes were collected: 35 patients with CRF and on regular maintenance dialysis, and a control group of 20 healthy persons for comparison, in the age group ranged between 25-70 years for both groups. Hemoglobin concentration, total red cells count, packed cell volume, total white blood cells count, neutrophils and lymphocytes differential count and platelets count were assessed by using Sysmex hematology analyzer. Data was analyzed through statistical package for social sciences (SPSS) version 24. Results recorded a significant decrease (p<0.05) in Hemoglobin concentration, total red cells count, packed cell volume and platelets count in patients with CRF compared to the healthy group. Although the total white blood cells count did not record any significant change, the differential count of lymphocytes decreased significantly (p<0.05), and the differential count of neutrophils increased without significant differences in patients with chronic renal failure CRF compared to healthy subjects. In conclusion, the present findings suggested that the chronic renal failure CRF had a negative effect on most of hematological parameters under study. Therefore, hematological parameters that need careful evaluation and management in chronic renal failure CRF patients.

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