Zagazig University Medical Journal


Background: Recently there are various non-skeletal diseases associated with vitamin D deficiency such as type 2 diabetes mellitus (T2DM). The main target of this study is to investigate whether there is any relationship between serum Vitamin D levels and glycemic control in type 2 diabetic patients.Methodology: The study was carried out in Najran University Hospital, this study involved 275 type 2 diabetic patients and 136 healthy control. Fasting blood glucose (FBG), HbA1c and 25(OH) vitamin D were analyzed.Results: The results showed (8%) of diabetic patients presented with severe Vitamin D deficiency, (27. 6%) presented with moderate deficiency, (19.6%) presented with insufficiency and (44.7%) presented with sufficient levels. HbA1c % and FBG were negatively correlated with Vitamin D levels. The mean levels of vitamin D showed a highly significant difference p > 0.001 between diabetic patients (27.84 ± 14.847 ng/ml) and healthy control subjects (53.99 ± 11.401 ng/ml), Also results showed a highly significant difference p > 0.001 in vitamin D level between controlled and uncontrolled diabetic patients the level of vitamin D was (46.4 ± 17.5; 28.2 ± 14.9) respectively.Conclusions: The findings suggested that there was a high incidence of vitamin D deficiency in type 2 diabetic patients and there was an inverse relationship between Vitamin D and FBG and HbA1c.



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