Future Dental Journal


Mesenchymal chondrosarcoma (MCS) is a rare high-grade variant of chondrosarcoma. MSC`s represent about 1% to 9% of chondrosarcomas. Less than 500 cases of MCS have been reported in literature, so far. As opposed to other variants, MSC develops outside of the bone in almost third of the cases. Pain and swelling are the most common symptoms at presentation. The overall prognosis of MSC is poor, with frequent distant metastases. Histopathologically, MCS typically exhibits a biphasic pattern consisting of both small cells, and islands of atypical cartilage. The immunohistochemical profile of this lesion overlaps with several other entities. Resection with wide margins is usually the treatment of choice. MCS is believed to be more responsive to chemotherapy and radiotherapy, than the other variants of chondrosarcoma. We are reporting a case of mesenchymal chondrosarcoma on the buccal alveolar mucosa of the first and second left mandibular molars, in a 25 year old female.