International Arab Journal of Dentistry


A dentigerous /follicular cyst is an odontogenic cyst associated with the crown of a non-erupted or partially erupted tooth. The exact histogenesis of this cyst remains unknown. Multiple signaling pathways and cellular modification are involved in its formation.The aim of this article is to report a case of a 9-year-old boy with a de novo EDA mutation, having an extreme oligodontia accompanied by the formation of a follicular cyst. This study hypothesizes the existence of causative relation between the EDA mutation and the cyst development around the impacted tooth.